We report the development of a scalable continuous Taylor vortex reactor for both UV and visible photochemistry. This builds on our recent report (Org. Process Res. Dev.2017,21, 1042) detailing a new approach to continuous visible photochemistry. Here, we expand this by showing that our approach can also be applied to UV photochemistry and that either UV or visible photochemistry can be scaled-up using our design. We have achieved scale-up in productivity of over 300× with a visible light photo-oxidation that requires oxygen gas and 10× with a UV-induced [2 + 2] cycloaddition obtaining scales of up to 7.45 kg day^–1 for the latter. Furthermore, we demonstrate that oxygen is efficiently taken up in the reactions of singlet O₂, and for the examples examined, that near-stoichiometric quantities of oxygen can be used with little loss of reactor productivity. Furthermore, our design should be scalable to a substantially larger size and have the potential for scaling-out with reactors in parallel.

中文翻译：

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可扩展的连续涡旋反应器，用于克至公斤级的紫外线和可见光化学反应

我们报告了针对紫外和可见光化学的可扩展的连续泰勒涡旋反应器的发展。这建立在我们最近的报告（有机化学过程RES。开发。2017年，21，详细介绍了一种新方法，以连续的可见光光化学1042）。在这里，我们通过展示我们的方法也可以应用于UV光化学，并且可以使用我们的设计扩大UV或可见光化学的范围来扩展此方法。我们已经通过需要氧气的可见光光氧化实现了300倍以上的生产率提升，而通过氧气诱导的[2 + 2]环加成实现了10倍规模生产率，后者高达7.45千克天– ¹。此外，我们证明单线态O ₂的反应中氧被有效吸收对于所检查的示例，可以使用接近化学计量的氧气，而不会损失反应器的生产率。此外，我们的设计应可扩展至更大的尺寸，并具有与电抗器并行扩展的潜力。