PURPOSE The purpose of this study was to analyze inferior vena cava (IVC) obstruction in Budd-Chiari syndrome (BCS) using rapid quantitative phase-contrast (PC) magnetic resonance (MR) imaging and compare the diagnostic efficacy of PC and MR venography (MRV) to explore the clinical prospects of applying PC quantitative diagnosis in IVC obstruction in BCS. MATERIALS AND METHODS PC quantitative data and MRV qualitative data obtained in 35 DSA-recognized inferior vena cava obstruction in BCS patients and 35 patients with liver focal lesions found in physical examination were analyzed and compared. RESULTS The areas under the ROC curve for diagnostic parameters related to PC quantitative parameters, including stroke volume, forward flow volume, absolute stroke volume, mean flux, stroke distance, mean velocity (MV), and peak velocity, were 0.7767, 0.7788, 0.7747, 0.7665, 0.9143, 0.9159, and 0.8947, respectively. The sensitivity, specificity, and accuracy of MV in the diagnosis of IVC obstruction were 88.57%, 85.71%, and 87.14%, respectively. For IVC obstruction in BCS, there was no significant difference between the diagnostic efficacy of MV (one of the quantitative parameters of PC) and that of MRV (P = 0.0768). CONCLUSION PC can be used to diagnose IVC obstruction in BCS and improve the understanding of hemodynamics of IVC obstruction in BCS.

中文翻译：

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Budd-Chiari综合征的下腔静脉阻塞：快速定量相差MRI和MRV的比较研究。

目的本研究的目的是使用快速定量相差（PC）磁共振（MR）成像分析Budd-Chiari综合征（BCS）的下腔静脉（IVC）阻塞，并比较PC和MR静脉造影的诊断功效（ （MRV），以探讨将PC定量诊断应用于BCS的IVC梗阻的临床前景。材料与方法分析并比较了35例DSA识别的BCS下腔静脉阻塞和35例经肝脏检查发现的肝局灶性病变患者的PC定量数据和MRV定性数据。结果ROC曲线下与PC定量参数相关的诊断参数的面积为0.7767，0，包括冲程量，正向流量，绝对冲程量，平均通量，冲程距离，平均速度（MV）和峰值速度。分别为7788、0.7747、0.7665、0.9143、0.9159和0.8947。MV在IVC阻塞诊断中的敏感性，特异性和准确性分别为88.57％，85.71％和87.14％。对于BCS中的IVC梗阻，MV（PC的定量参数之一）和MRV（P = 0.0768）的诊断效力之间没有显着差异。结论PC可用于诊断BCS中的IVC阻塞，并增进对BCS中IVC阻塞的血流动力学的了解。MV（PC的定量参数之一）和MRV的诊断效力之间无显着差异（P = 0.0768）。结论PC可用于诊断BCS中的IVC阻塞，并增进对BCS中IVC阻塞的血流动力学的了解。MV（PC的定量参数之一）和MRV的诊断效力之间无显着差异（P = 0.0768）。结论PC可用于诊断BCS中的IVC阻塞，并增进对BCS中IVC阻塞的血流动力学的了解。