Pulmonary hypertension (PH) describes a heterogeneous set of diseases associated with increased morbidity and mortality, regardless of the aetiology [1–4]. The gold standard for diagnosing and phenotyping PH remains invasive measurement via right heart catheterisation [5]. Noninvasive estimation of pulmonary haemodynamics is an attractive alternative to reduce procedural risk and to more broadly study patient subsets who do not uniformly undergo right heart catheterisation for evaluation of PH (e.g. most patients with PH due to left heart disease) [5–7]. However, imperfect correlations between invasive and noninvasive measurements limit broad adoption of noninvasive strategies for the evaluation of PH [8–13]. The study by Obokata and co-workers published in this issue of the European Respiratory Journal significantly contributes to the field of noninvasive prediction of haemodynamics during exercise http://bit.ly/2svY7TP

中文翻译：

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漂浮看不见的天鹅：血液动力学的无创预测

肺动脉高压 (PH) 描述了一组与发病率和死亡率增加相关的异质性疾病，无论其病因如何 [1-4]。诊断和表型 PH 的金标准仍然是通过右心导管插入术进行有创测量 [5]。肺血流动力学的无创评估是一种有吸引力的替代方法，可降低手术风险并更广泛地研究未统一接受右心导管插入术以评估 PH 的患者亚群（例如，大多数左心疾病导致的 PH 患者）[5-7]。然而，侵入性和非侵入性测量之间的不完美相关性限制了广泛采用非侵入性策略来评估 PH [8-13]。