COPD is one of the leading causes of mortality worldwide [1]. Pulmonary hypertension has been associated with reduced survival among individuals with COPD [2] and is an independent risk factor for mortality following acute exacerbations of COPD (AECOPD) [3]. Measurement of the pulmonary artery to aorta (PA:A) ratio by computed tomography (CT) and assessment of pulmonary artery enlargement (PA:A >1) outperforms echocardiography in identifying pulmonary hypertension in severe COPD [4], and pulmonary artery enlargement has been independently associated with risk for total and severe AECOPD in two large prospective COPD cohorts [5]. Pulmonary artery enlargement on chest CT imaging is independently associated with all-cause mortality in moderate–severe COPD, after adjustment for other known risk factors for COPD mortality and cardiovascular disease http://bit.ly/2rdYOR1

中文翻译：

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中度至重度 COPD 患者的肺动脉扩张和死亡风险：来自 COPDGene 的结果

COPD是世界范围内导致死亡的主要原因之一[1]。肺动脉高压与 COPD 患者的生存率降低有关 [2]，并且是 COPD 急性加重 (AECOPD) 后死亡的独立危险因素 [3]。通过计算机断层扫描 (CT) 测量肺动脉与主动脉 (PA:A) 的比率和评估肺动脉扩大 (PA:A >1) 在识别严重 COPD 中的肺动脉高压方面优于超声心动图 [4]，并且肺动脉扩大具有在两个大型前瞻性 COPD 队列中，与总体和重度 AECOPD 风险独立相关[5]。胸部 CT 影像上的肺动脉扩张与中重度 COPD 的全因死亡率独立相关，