Neurotensin (NTS) is a neuropeptide neurotransmitter expressed in the central and peripheral nervous systems. Many studies over the years have revealed a number of roles for this neuropeptide in body temperature regulation, feeding, analgesia, ethanol sensitivity, psychosis, substance use, and pain. This review provides a general survey of the role of neurotensin with a focus on modalities that we believe to be particularly relevant to the study of reward. We focus on NTS signaling in the ventral tegmental area, nucleus accumbens, lateral hypothalamus, bed nucleus of the stria terminalis, and central amygdala. Studies on the role of NTS outside of the ventral tegmental area are still in their relative infancy, yet they reveal a complex role for neurotensinergic signaling in reward-related behaviors that merits further study. This article is part of the special issue on 'Neuropeptides'.

中文翻译：

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奖励过程中的神经降压素。

神经降压素（NTS）是在中枢神经系统和周围神经系统中表达的神经肽神经递质。多年来的许多研究表明，该神经肽在体温调节，进食，镇痛，乙醇敏感性，精神病，药物使用和疼痛中具有多种作用。这篇综述提供了关于神经降压素作用的一般调查，重点是我们认为与奖赏研究特别相关的方式。我们专注于腹侧被盖区，伏隔核，下丘脑外侧，终末纹的床核和中央杏仁核的NTS信号传导。关于NTS在腹侧被盖区以外的作用的研究仍处于初期阶段，但它们揭示了神经降压能信号在奖励相关行为中的复杂作用，值得进一步研究。