Studies uncovering the cellular mechanisms of adaptation to varying oxygen levels were recognized with the 2019 Nobel Prize in Physiology or Medicine. Here, we focus on the remarkable parallels between the pathways regulating oxygen availability and those driving rare neuroendocrine tumours, phaeochromocytomas and paragangliomas, and discuss the translational implications of this connection.

中文翻译：

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认识到嗜铬细胞瘤和神经节瘤中的缺氧。

揭示了适应不同氧气水平的细胞机制的研究获得了2019年诺贝尔生理学或医学奖。在这里，我们关注调节氧气供应的途径与驱动罕见神经内分泌肿瘤，嗜铬细胞瘤和副神经节瘤的途径之间的显着相似之处，并讨论这种联系的翻译意义。