Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative.,PLOS Biology

当前位置： X-MOL 学术 › PLOS Biol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative.
PLOS Biology ( IF 7.8 ) Pub Date : 2020-02-11 , DOI: 10.1371/journal.pbio.3000576
Daniel Strech _{1,

2} , Tracey Weissgerber _{1,

2} , Ulrich Dirnagl _{1,

2} ,

Affiliation

The reproducibility crisis triggered worldwide initiatives to improve rigor, reproducibility, and transparency in biomedical research. There are many examples of scientists, journals, and funding agencies adopting responsible research practices. The QUEST (Quality-Ethics-Open Science-Translation) Center offers a unique opportunity to examine the role of institutions. The Berlin Institute of Health founded QUEST to increase the likelihood that research conducted at this large academic medical center would be trustworthy, useful for scientists and society, and ethical. QUEST researchers perform "science of science" studies to understand problems with standard practices and develop targeted solutions. The staff work with institutional leadership and local scientists to incentivize and support responsible practices in research, funding, and hiring. Some activities described in this paper focus on the institution, whereas others may benefit the national and international scientific community. Our experience, approaches, and recommendations will be informative for faculty leadership, administrators, and researchers interested in improving scientific practice.

中文翻译：

通过创新和全面的机构举措提高生物医学研究的可信度、有用性和道德规范。

可重复性危机引发了全球范围内提高生物医学研究严谨性、可重复性和透明度的举措。科学家、期刊和资助机构采取负责任的研究实践的例子有很多。 QUEST（质量-伦理-开放科学-翻译）中心提供了一个独特的机会来检验机构的作用。柏林健康研究所创立了 QUEST，旨在提高在这个大型学术医学中心进行的研究可信、对科学家和社会有用且符合道德的可能性。 QUEST 研究人员进行“科学的科学”研究，以了解标准实践中的问题并开发有针对性的解决方案。工作人员与机构领导层和当地科学家合作，激励和支持研究、资助和招聘方面负责任的做法。本文描述的一些活动侧重于该机构，而其他活动则可能使国家和国际科学界受益。我们的经验、方法和建议将为有兴趣改进科学实践的教师领导、管理人员和研究人员提供信息。

更新日期：2020-03-02

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11