Pathogens are organisms that are capable of invading living bodies, often causing disease. Pathogens are inherently harmful; however, a new trend has recently emerged suggesting that pathogens could act as potential therapeutic agents. It became increasingly important to candidate pathogens for beneficial use in medicine and biological studies. Cellular barriers and immune system are powerful obstacles; however, pathogens are able to overcome these defenses, and targeting strategies, using genetically engineered pathogens, can reduce potentially damaging effects of the molecule to be delivered. The central nervous system requires more focused studies in this respect, using recently developed techniques in molecular science, such as genome manipulation.

中文翻译：

---

病原体完全有害还是无用？

病原体是能够侵入活体并经常引起疾病的生物。病原体具有内在的危害；然而，最近出现了一种新趋势，表明病原体可以作为潜在的治疗剂。在医学和生物学研究中有益使用候选病原体变得越来越重要。细胞屏障和免疫系统是强大的障碍。但是，病原体能够克服这些防御因素，使用基因工程病原体的靶向策略可以减少所传递分子的潜在破坏作用。中枢神经系统在这方面需要使用分子科学方面最近开发的技术（例如基因组操作）进行更集中的研究。