H₂Se has been widely applied, and its release will cause serious human health and environmental effects. It is urgent to develop facile tool and reliable method for the determination of H₂Se. Here, we introduce a concisely synthesized molecular HBT-Se, with a specially designed H₂Se trapper 2-(iodomethyl)benzoate and a typical ESIPT fluorophore. The free HBT-Se exhibited blue fluorescence owing to the blocked ESIPT (exited state intramolecular proton transfer) process, while the 2-(iodomethyl)benzoate group could undergo a cascade reaction with H₂Se, unblocking the ESIPT process and bathochromically shifting fluorescence response. The sensing mechanism was also rigorously verified by ¹H, ⁷⁷Se NMR and MS analyses. Additionally, HBT-Se features a sensitive, selective and quantitative determination of H₂Se. With these satisfied properties, HBT-Se was further applied as a paper-based sensor for detection of gaseous H₂Se, and the enhanced performances of HBT-Se will promote its potential value in further study of H₂Se in environmental pollutant.

H ₂ Se已被广泛应用，其释放会严重影响人类健康和环境。迫切需要开发一种简便的工具和可靠的方法来测定H ₂ Se。在这里，我们介绍了一种简洁合成的分子HBT-Se，它具有经过特殊设计的H ₂ Se捕集剂2-（碘甲基）苯甲酸酯和典型的ESIPT荧光团。游离的HBT-Se由于被封闭的ESIPT（分子内质子转移状态）过程而呈现蓝色荧光，而2-（碘甲基）苯甲酸酯基团可能与H ₂发生级联反应硒，阻止ESIPT过程，并通过红移改变荧光响应。还通过¹ H，⁷⁷ Se NMR和MS分析严格地验证了感应机理。此外，HBT-Se具有H ₂ Se的灵敏，选择性和定量测定的功能。凭借这些令人满意的性能，HBT-Se进一步被用作纸质传感器来检测气态H ₂ Se，并且HBT-Se的增强性能将促进其在环境污染物中H ₂ Se的进一步研究中的潜在价值。