Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Influence of age, lesion volume, and damage to dorsal versus ventral streams to viewer- and stimulus-centered hemispatial neglect in acute right hemisphere stroke.
Cortex ( IF 3.2 ) Pub Date : 2020-02-10 , DOI: 10.1016/j.cortex.2019.12.030 Adrian Suarez 1 , Sadhvi Saxena 1 , Kenichi Oishi 2 , Kumiko Oishi 2 , Alexandra Walker 1 , Chris Rorden 3 , Argye E Hillis 4
Cortex ( IF 3.2 ) Pub Date : 2020-02-10 , DOI: 10.1016/j.cortex.2019.12.030 Adrian Suarez 1 , Sadhvi Saxena 1 , Kenichi Oishi 2 , Kumiko Oishi 2 , Alexandra Walker 1 , Chris Rorden 3 , Argye E Hillis 4
Affiliation
We studied 156 individuals with acute, right hemisphere ischemic stroke on a battery of hemispatial neglect tests to distinguish between viewer-centered and stimulus-centered neglect and MRI diffusion weighted imaging. We identified the relative contributions of age, total lesion volume, and damage to subcortical and cortical grey matter regions as well as white matter tracts to both the severity and presence of significant viewer-centered and stimulus-centered neglect, using multivariable regression tests. We found that age, volume of lesion, and percent damage to the regions of interest were each independently associated with the severity of viewer-centered neglect (r2 = .31; p < .0001). However, only age (t = 3.20; p = .002) and percent damage to the angular gyrus (t = 2.63, p = .010), a dorsal stream area, predicted severity of viewer-centered neglect independently of the other variables. The same variables predicted the presence of significant viewer-centered neglect. In contrast, these variables did not significantly predict the severity of stimulus-centered neglect. However, we found that percent damage to ventral stream regions of interest (middle temporal gyrus, inferior temporal gyrus, fusiform gyrus, inferior frontal occipital gyrus, sagittal stratum, along with total infarct volume were associated with the presence of significant stimulus-centered neglect (pseudo r2 = .70, p < .0004). Only percent damage to right inferior temporal gyrus predicted stimulus-centered neglect independently of the other variables (p = .018).
中文翻译：
年龄、病变体积以及背侧与腹侧流的损伤对急性右半球中风中以观察者和刺激为中心的半侧空间忽视的影响。
我们对 156 名患有急性右半球缺血性中风的个体进行了一系列半空间忽视测试，以区分以观察者为中心和以刺激为中心的忽视以及 MRI 扩散加权成像。我们使用多变量回归测试确定了年龄、总病变体积以及皮质下和皮质灰质区域以及白质束的损伤对以观察者为中心和以刺激为中心的忽视的严重性和存在的相对贡献。我们发现，年龄、病变体积和感兴趣区域的损伤百分比均与以观察者为中心的忽视的严重程度独立相关（r2 = .31；p < .0001）。然而，只有年龄（t = 3.20；p = .002）和角回损伤百分比（t = 2.63，p = .010）（背流区域）可以独立于其他变量预测以观看者为中心的忽视的严重程度。相同的变量预测了以观众为中心的重大忽视的存在。相反，这些变量并不能显着预测以刺激为中心的忽视的严重程度。然而，我们发现腹侧流感兴趣区域（颞中回、颞下回、梭状回、额枕下回、矢状层以及总梗死体积）的损伤百分比与显着的以刺激为中心的忽视的存在相关。伪 r2 = .70，p < .0004）。仅右颞下回损伤百分比预测独立于其他变量的以刺激为中心的忽视（p = .018）。
更新日期：2020-02-10
中文翻译：
年龄、病变体积以及背侧与腹侧流的损伤对急性右半球中风中以观察者和刺激为中心的半侧空间忽视的影响。
我们对 156 名患有急性右半球缺血性中风的个体进行了一系列半空间忽视测试，以区分以观察者为中心和以刺激为中心的忽视以及 MRI 扩散加权成像。我们使用多变量回归测试确定了年龄、总病变体积以及皮质下和皮质灰质区域以及白质束的损伤对以观察者为中心和以刺激为中心的忽视的严重性和存在的相对贡献。我们发现，年龄、病变体积和感兴趣区域的损伤百分比均与以观察者为中心的忽视的严重程度独立相关（r2 = .31；p < .0001）。然而，只有年龄（t = 3.20；p = .002）和角回损伤百分比（t = 2.63，p = .010）（背流区域）可以独立于其他变量预测以观看者为中心的忽视的严重程度。相同的变量预测了以观众为中心的重大忽视的存在。相反，这些变量并不能显着预测以刺激为中心的忽视的严重程度。然而，我们发现腹侧流感兴趣区域（颞中回、颞下回、梭状回、额枕下回、矢状层以及总梗死体积）的损伤百分比与显着的以刺激为中心的忽视的存在相关。伪 r2 = .70，p < .0004）。仅右颞下回损伤百分比预测独立于其他变量的以刺激为中心的忽视（p = .018）。
京公网安备 11010802027423号