Synthesis of 3-phosphinoylbenzofurans via electrophilic phosphination cyclization,Organic Chemistry Frontiers

当前位置： X-MOL 学术 › Org. Chem. Front. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Synthesis of 3-phosphinoylbenzofurans via electrophilic phosphination cyclization
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2020/01/23 , DOI: 10.1039/c9qo01502g
Jia Wang _{1,

2,

3,

4} , Yun-Jing Deng _{1,

2,

3,

4} , Xin-Xin Yan _{2,

3,

4,

5} , Yu-Jie Liu _{2,

3,

4,

5} , Chun-Po Ge _{1,

2,

3,

4} , Yunhui Yan _{1,

2,

3,

4} , Shujun Chao _{1,

2,

3,

4} , Ping-Xin Zhou _{1,

2,

3,

4}

Affiliation

An expedient strategy for the synthesis of 3-phosphinoylbenzofurans through a cascade electrophilic phosphination cyclization has been presented. This sequential process was induced by phosphenium-cations under mild and metal-free conditions. The reaction can be scaled up to gram quantities with an excellent yield. Additionally, the obtained arylphosphine oxide product can be reduced to phosphine, which could coordinate with the transition metals ruthenium and palladium, acting as potential ligands for other important chemical reactions.

中文翻译：

亲电磷酸环化反应合成3-膦酰基苯并呋喃

提出了通过级联亲电性磷酸化环合反应合成3-膦酰基苯并呋喃的简便策略。该顺序过程是由磷阳离子在温和且不含金属的条件下诱导的。该反应可以按比例放大至克量，并具有优异的产率。另外，所获得的芳基膦氧化物产物可以还原为膦，其可以与过渡金属钌和钯配位，充当其他重要化学反应的潜在配体。

更新日期：2020-02-18

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11