Transition metal- and solvent-free double hydroboration of nitriles,Green Chemistry

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Transition metal- and solvent-free double hydroboration of nitriles
Green Chemistry ( IF 9.3 ) Pub Date : 2020/01/29 , DOI: 10.1039/c9gc04260a
Deepika Bedi _{1,

2,

3,

4} , Aneelman Brar _{1,

2,

3,

4} , Michael Findlater _{1,

2,

3,

4}

Affiliation

A highly efficient, room temperature double hydroboration of nitriles under transition metal-free and solvent-free conditions is reported. Sodium triethylborohydride is used as a catalyst and yields up to 99% are disclosed. Mechanistic studies reveal the reaction proceeds in a stepwise manner with initial formation of a boryl-imine which undergoes a second hydroboration to afford a diborylated amine product.

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