The aim of this study was to fabricate flowable resin composites, by incorporating Farnesol loaded Halloysite Nanotubes (Fa-HNT) as a filler and evaluate their physicochemical as well as biological properties. Chemical and morphological characterization of antibacterial filler, Fa-HNT were performed using Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Transmission Electron Microscope (TEM), Scanning Electron Microscope (SEM). The antibacterial filler was mixed into composite material consisting of methacrylate monomers and dental glass fillers at concentrations of 1–20% (wt./wt.). It was observed that addition of mass fractions of Fa-HNT causes enhancement of compressive strength as well as flexural modulus of the composite. However, it significantly decreases flexural strength and degree of conversion. A significant antibacterial activity of dental composite was observed with increase in the area of zone of inhibition against the strains of Streptococcus mutans (S. mutans). There was no cytotoxicity observed by Fa-HNT resin composites on NIH-3T3 (mouse embryonic fibroblast cells) cell lines. A favourable integration of antibacterial filler with significant mechanical properties was achieved at concentrations from 7 to 13 wt% of Fa-HNT in dental composites, which is desirable in dentistry.

这项研究的目的是通过掺入法呢醇负载的埃洛石纳米管（Fa-HNT）作为填充剂并评估其理化和生物学特性来制造可流动的树脂复合材料。使用傅立叶变换红外光谱（FTIR），X射线衍射（XRD），透射电子显微镜（TEM），扫描电子显微镜（SEM）对抗菌填料Fa-HNT进行化学和形态表征。将抗菌填料以1–20％（wt./wt。）的浓度混合到由甲基丙烯酸酯单体和牙科玻璃填料组成的复合材料中。观察到Fa-HNT的质量分数的添加引起复合材料的抗压强度以及挠曲模量的提高。但是，它显着降低了弯曲强度和转化度。变形链球菌（变形链球菌）。Fa-HNT树脂复合材料在NIH-3T3（小鼠胚胎成纤维细胞）细胞系上未观察到细胞毒性。在牙科复合物中，Fa-HNT的浓度为7至13 wt％时，可以实现具有显着机械性能的抗菌填料的良好结合，这在牙科领域是理想的。