Currently, the emergence of a novel human coronavirus, SARS-CoV-2, has become a global health concern causing severe respiratory tract infections in humans. Human-to-human transmissions have been described with incubation times between 2-10 days, facilitating its spread via droplets, contaminated hands or surfaces. We therefore reviewed the literature on all available information about the persistence of human and veterinary coronaviruses on inanimate surfaces as well as inactivation strategies with biocidal agents used for chemical disinfection, e.g. in healthcare facilities. The analysis of 22 studies reveals that human coronaviruses such as Severe Acute Respiratory Syndrome (SARS) coronavirus, Middle East Respiratory Syndrome (MERS) coronavirus or endemic human coronaviruses (HCoV) can persist on inanimate surfaces like metal, glass or plastic for up to 9 days, but can be efficiently inactivated by surface disinfection procedures with 62-71% ethanol, 0.5% hydrogen peroxide or 0.1% sodium hypochlorite within 1 minute. Other biocidal agents such as 0.05-0.2% benzalkonium chloride or 0.02% chlorhexidine digluconate are less effective. As no specific therapies are available for SARS-CoV-2, early containment and prevention of further spread will be crucial to stop the ongoing outbreak and to control this novel infectious thread.

中文翻译：

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冠状病毒在无生命表面上的持久性及其用杀生物剂灭活。

目前，一种新型人类冠状病毒SARS-CoV-2的出现已成为全球健康问题，导致人类严重呼吸道感染。人与人之间的传播已被描述为潜伏期为 2-10 天，这有助于其通过飞沫、受污染的手或表面传播。因此，我们回顾了有关人类和兽医冠状病毒在无生命表面上的持久性以及用于化学消毒的杀菌剂的灭活策略的所有可用信息的文献，例如在医疗机构中。对 22 项研究的分析表明，人类冠状病毒，如严重急性呼吸系统综合症 (SARS) 冠状病毒、中东呼吸系统综合症 (MERS) 冠状病毒或地方性人类冠状病毒 (HCoV) 可以在金属等无生命的表面上持续存在，玻璃或塑料长达 9 天，但可在 1 分钟内使用 62-71% 乙醇、0.5% 过氧化氢或 0.1% 次氯酸钠进行表面消毒程序有效灭活。其他杀生物剂如 0.05-0.2% 苯扎氯铵或 0.02% 氯己定二葡萄糖酸盐效果较差。由于没有针对 SARS-CoV-2 的特定疗法，早期遏制和防止进一步传播对于阻止持续爆发和控制这种新型传染线至关重要。