Carbon monoxide (CO) is an inorganic chemical compound that can bind with hemoglobin with highly toxic effects. In living organisms, it is produced endogenously during the degradation of heme by oxygenase, which occurs in three isoforms: HO-1, HO-2 and HO-3. CO can play an important role in the regulation of many physiological functions. Carbon Oxide Releasing Molecules (CORMs) are a novel group of chemical compounds capable of controlled CO release directly in tissues or organs. This release depends on concentration, pH, solvent type and temperature. The biological role and the therapeutic potential of different CORMs is not always well demonstrated. However, this mini review summarizes the various function of these compounds.

中文翻译：

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一氧化碳及其供体化学和生物学特性。

一氧化碳（CO）是一种无机化合物，可与血红蛋白结合并具有剧毒作用。在活生物体中，它是在氧合酶降解血红素的过程中内生产生的，氧合酶以三种同工型出现：HO-1，HO-2和HO-3。一氧化碳可以在许多生理功能的调节中发挥重要作用。二氧化碳释放分子（CORM）是一类新颖的化合物，能够直接控制CO在组织或器官中的释放。该释放取决于浓度，pH，溶剂类型和温度。并非总是很好地证明了不同CORM的生物学作用和治疗潜力。但是，本微型综述总结了这些化合物的各种功能。