Abstract

This paper describes the optimization and in house validation of an electroanalytical method for the determination of 2,4,6-trichlorophenol (2,4,6-TCP) in beverages for the first time. Cyclic voltammetry and square wave voltammetry techniques, 0.1 mol L⁻¹ Britton–Robinson buffer (pH 8.0) and boron-doped diamond electrode were used for this purpose. The system was optimized and the obtained analytical curves presented good linearity in the concentration range investigated; moreover, the linear model did not present a lack-of-fit. The limits of detection and quantification (0.15 μmol L⁻¹ and 0.46 μmol L⁻¹, respectively) of the used method were low. In addition, this method presented good accuracy and precision (recovery rates between 90.0% and 118.0% and relative standard deviation values in the range of 0.74% to 1.51%). Thus, it was suggested that the developed electroanalytical method could be used for the determination of 2,4,6-TCP in beverages and presented advantages, such as speed, low cost, and low consumption of toxic reagents, compared with traditional methods.

中文翻译：

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伏安法测定饮料中的2,4,6-三氯酚含量：优化和验证研究

摘要

本文首次介绍了一种用于分析饮料中2,4,6-三氯苯酚（2,4,6-TCP）的电分析方法的优化和内部验证。为此，使用了循环伏安法和方波伏安法，0.1 mol L ^-1的Britton-Robinson缓冲液（pH 8.0）和掺硼金刚石电极。对系统进行了优化，所获得的分析曲线在所研究的浓度范围内表现出良好的线性。此外，线性模型没有出现拟合不足。检测和定量限（0.15μmolL ^-1和0.46μmolL ^-1，分别）的使用率低。此外，该方法具有良好的准确性和精密度（回收率在90.0％至118.0％之间，相对标准偏差值在0.74％至1.51％的范围内）。因此，建议开发的电分析方法可用于饮料中2,4,6-TCP的测定，与传统方法相比，具有速度快，成本低，有毒试剂消耗少等优点。