Abstract

α-Form zinc phthalocyanine (ZnPc), a kinetically favorable form of ZnPc, is an efficient photosensitizer for photodynamic cancer therapy, especially when it is formed into nanowires (NWs), which have high water dispersibility. To take full advantage of this material, it is necessary to selectively grow kinetically favorable α-form ZnPc NWs over thermodynamically favorable β-form ZnPc NWs. The present study reports the selective growth of kinetically favorable α-form ZnPc NW crystals by a physical vapor transport method with flow rate control of the carrier gas. The flow rate is key for the dominant growth of α-form ZnPc NWs, thus enabling control of the crystal size, which critically affects the stability of ZnPc crystals. The yield of α-form ZnPc NWs was over 98% at a flow rate of 2000 sccm of Ar carrier gas. This approach could be applied for various Pc molecules, including copper phthalocyanine (CuPc). Our findings might contribute to the development of novel strategies for the selective growth of high-quality kinetically favorable crystals with a specific structure and provide great opportunities for their various practical applications.

中文翻译：

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通过物理气相传输的流量控制选择性生长α-形式的酞菁锌纳米线晶体

摘要

α-形式的酞菁锌（ZnPc）是ZnPc的动力学上有利的形式，是用于光动力癌症治疗的有效光敏剂，特别是当它形成具有高水分散性的纳米线（NWs）时。为了充分利用这种材料，必须选择性地生长动力学上有利的α型ZnPc NW，而不是热力学上良好的β形ZnPc NW。本研究报告了通过物理气相传输方法并控制载气的流速，选择性生长了动力学上有利的α型ZnPc NW晶体。流速对于α型ZnPc NW的主要生长至关重要，因此可以控制晶体尺寸，从而严重影响ZnPc晶体的稳定性。在Ar载气流量为2000 sccm时，α型ZnPc NW的产率超过98％。该方法可应用于各种Pc分子，包括酞菁铜（CuPc）。我们的发现可能有助于开发新策略，以选择性生长具有特定结构的高质量动力学上有利的晶体，并为其各种实际应用提供巨大机会。