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The KRAS-BCAA-BCAT2 axis in PDAC development.
Nature Cell Biology ( IF 21.3 ) Pub Date : 2020-02-06 , DOI: 10.1038/s41556-020-0467-2 Mattia Falcone 1 , Oliver D K Maddocks 1
Nature Cell Biology ( IF 21.3 ) Pub Date : 2020-02-06 , DOI: 10.1038/s41556-020-0467-2 Mattia Falcone 1 , Oliver D K Maddocks 1
Affiliation
Understanding the metabolic rewiring of pancreatic ductal adenocarcinoma is an emerging strategy for identifying cancer-associated liabilities and improving treatment. A new study now elucidates the function of the transaminase BCAT2 in the early stages of tumor development, providing insights that could stimulate novel therapeutic strategies.
中文翻译:
PDAC开发中的KRAS-BCAA-BCAT2轴。
了解胰腺导管腺癌的代谢重新连接是一种识别癌症相关负债并改善治疗的新兴策略。现在一项新的研究阐明了转氨酶BCAT2在肿瘤发展的早期阶段的功能,提供了可以激发新的治疗策略的见解。
更新日期:2020-02-06
中文翻译:
PDAC开发中的KRAS-BCAA-BCAT2轴。
了解胰腺导管腺癌的代谢重新连接是一种识别癌症相关负债并改善治疗的新兴策略。现在一项新的研究阐明了转氨酶BCAT2在肿瘤发展的早期阶段的功能,提供了可以激发新的治疗策略的见解。