BACKGROUND Limb salvage surgery is becoming increasingly popular after tumor resection in the lower extremity. Biological reconstruction and use of megaprosthesis are main methods for malignant bone tumors of the proximal femur, which remain controversial due to short- and long-term complication in the proximal femur. Tumor-bearing bone treated by liquid nitrogen is one of biological reconstruction. This study aimed to evaluate the mid- and long-term functional outcomes and complications in patients treated with frozen autograft-prosthesis composite (FAPC) reconstructions in the proximal femur. METHODS This retrospective study included 19 patients (10 women, 9 men) with malignant tumors of the proximal femur who underwent tumor-wide resection and FAPC reconstruction (mean age, 46 years; range, 9-77 years). The mean follow-up period of 69 months (range, 9-179 months). Functional outcomes, oncological outcome and complications were evaluated by Musculoskeletal Tumor Society score, clinical and radiological examinations. RESULTS The overall survival rate was 68.4%, and the mean Musculoskeletal Tumor Society functional score was 26.4 points (88%). FAPC survival rates were 100 and 50% at 5 and 10 years, respectively. Five of the 19 patients (26%) had complications: 2 required prosthesis removal and 2 developed a deep infection around acetabular. Wear of the acetabulum occurred in 2 cases, while disease recurrence was occurred in 1 case. There were no cases of greater trochanter avulsion, obvious absorption around frozen bone, prosthesis loosening or leg length discrepancy. CONCLUSIONS Due to without femoral osteotomy, this technique features satisfactory functional outcome and provide biomechanical stability that is comparable to those of other methods of biological reconstruction or megaprosthesis.

中文翻译：

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股骨近端恶性骨肿瘤的椎弓根冷冻自体假体复合材料重建物。

背景技术在下肢肿瘤切除之后，肢体抢救手术变得越来越普遍。生物重建和巨型假体的使用是股骨近端恶性骨肿瘤的主要方法，由于股骨近端的短期和长期并发症，该方法仍存在争议。液氮处理的荷瘤骨是生物学重建方法之一。本研究旨在评估股骨近端冷冻自体假体复合材料（FAPC）重建治疗患者的中长期功能结局和并发症。方法这项回顾性研究包括19例股骨近端恶性肿瘤患者（10例女性，9例男性），他们接受了全肿瘤切除和FAPC重建（平均年龄46岁；范围9-77岁）。平均随访期为69个月（范围9-179个月）。通过肌肉骨骼肿瘤学会评分，临床和放射学检查评估功能结局，肿瘤结局和并发症。结果总生存率为68.4％，平均肌肉骨骼肿瘤学会功能评分为26.4分（88％）。FAPC在5年和10年时的存活率分别为100％和50％。19例患者中有5例（26％）有并发症：2例需要摘除假体，2例在髋臼周围发生深部感染。髋臼磨损2例，疾病复发1例。没有大转子撕脱，冷冻骨周围明显吸收，假体松动或腿长差异的情况。结论由于没有进行股骨截骨术，