BACKGROUND Antimicrobial resistance (AMR) is an escalating global health issue with complex and dynamic interdependencies, high uncertainty and decision stakes, multiple drivers and stakeholders with diverse values and interests, and various aspects and outcomes. Addressing and combating this critical global challenge requires the formation and establishment of an interdisciplinary research approach that goes beyond the biosciences principally concerned with antimicrobial resistance to include other relevant natural and social sciences. The objective of this study will be to review and map existing social science knowledge and literature relating to antimicrobial resistance. METHODS The review team will undertake the scoping review using the Arksey and O'Malley methodological framework and also the Joanna Briggs Institute methods manual. Publications in English (from 1998 onwards) will be searched using several databases including PubMed/MEDLINE, Web of Science, Scopus, Anthropological Plus, Sociological Abstracts, International Bibliography of the Social Sciences (IBSS), PsycINFO and EconLit. Grey literature will also be searched (e.g. Google Scholar). Two reviewers will independently screen all citations, full-text articles, and abstract data. Publication types will include original articles, editorials, commentaries, protocols, and books in the social science research literature on AMR. All study designs (quantitative, qualitative, and mixed-methods) will be included. A PRISMA Flow Diagram of search and study selection will be used to report final figures on included and excluded studies. To provide a descriptive summary of the literature, data will be collated, stored, and charted using Microsoft Excel software. The analysis will also involve identifying themes and gaps in the existing literature and summarizing, describing and displaying all pertinent information using thematic construction approaches including qualitative content analysis methods. DISCUSSION This protocol describes a systematic method to identify, map, and synthesize social science research evidence on antimicrobial resistance. By mapping evidence and identifying potential knowledge gaps where further research is warranted, the resulting scoping review will provide useful insights for the design, implementation, and reorientation of future research agendas on AMR at multiple levels. Systematic review registration: This protocol has been registered with the Open Science Framework (OSF): https://osf.io/hyaem.

中文翻译：

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社会科学研究对抗菌素耐药性的贡献：范围审查协议。


背景技术抗菌素耐药性（AMR）是一个不断升级的全球健康问题，具有复杂和动态的相互依赖性、高度的不确定性和决策风险、具有不同价值观和利益的多个驱动因素和利益相关者以及各个方面和结果。应对和应对这一严峻的全球挑战需要形成和建立跨学科研究方法，该方法超越主要关注抗菌素耐药性的生物科学，包括其他相关的自然科学和社会科学。本研究的目的是回顾和绘制与抗菌素耐药性相关的现有社会科学知识和文献。方法 审查小组将使用 Arksey 和 O'Malley 方法框架以及 Joanna Briggs Institute 方法手册进行范围界定审查。英文出版物（自 1998 年起）将使用多个数据库进行检索，包括 PubMed/MEDLINE、Web of Science、Scopus、Anthropological Plus、Sociological Abstracts、International Bibliography of the Social Sciences (IBSS)、PsycINFO 和 EconLit。灰色文献也会被搜索（例如谷歌学术）。两名审稿人将独立筛选所有引文、全文文章和摘要数据。出版物类型将包括抗微生物药物耐药性社会科学研究文献中的原创文章、社论、评论、方案和书籍。所有研究设计（定量、定性和混合方法）都将包括在内。检索和研究选择的 PRISMA 流程图将用于报告纳入和排除研究的最终数据。为了提供文献的描述性摘要，将使用 Microsoft Excel 软件对数据进行整理、存储和绘制图表。 分析还将涉及确定现有文献中的主题和差距，并使用主题构建方法（包括定性内容分析方法）总结、描述和显示所有相关信息。讨论 本协议描述了一种识别、绘制和综合抗菌素耐药性社会科学研究证据的系统方法。通过绘制证据并确定需要进一步研究的潜在知识差距，由此产生的范围界定审查将为多个层面的抗微生物药物耐药性未来研究议程的设计、实施和重新定位提供有用的见解。系统审查注册：该协议已在开放科学框架（OSF）中注册：https://osf.io/hyaem。