Collagen and chitosan, used for the preparation of sponges, were isolated from the residues of aquatic origin, and co-adjuvant material alginate was added. All sponges are light-colored, but those formulated with chitosan have a yellow hue. The chemical interaction between the components was confirmed by Fourier-transform infrared spectroscopy. The porosity of the sponges is in the range from 88 to 95%. The sponges based on collagen/chitosan/alginate exhibited the highest capacity for absorption in water at 25 °C, with values of up to 2838%. Collagen-chitosan sponges have less rigidity and mechanical strength than collagen-alginate sponges. Collagen-alginate sponges contained the highest maximum stress and Young's modulus, with values of 0.5463 MPa and 0.0086 MPa, respectively. Collagen sponges with chitosan have a greater elongation at break (6.1566%). The sponges with the highest antimicrobial activity were collagen-chitosan mixtures, with inhibition zones of up to 46.62% against Staphylococcus aureus. We anticipate that the sponges based on fish collagen and shrimp chitosan can serve as an alternative of biomaterial for the healing of cutaneous wounds due to their mechanical and antibacterial properties.

从水生起源的残留物中分离出用于制备海绵的胶原蛋白和壳聚糖，并加入辅助助剂藻酸盐。所有海绵均为浅色，但使用壳聚糖配制的海绵具有黄色调。组分之间的化学相互作用通过傅里叶变换红外光谱法确认。海绵的孔隙率在88％至95％的范围内。基于胶原蛋白/壳聚糖/藻酸盐的海绵在25°C的水中表现出最高的吸收能力，其值高达2838％。胶原-壳聚糖海绵比胶原-海藻酸钠海绵具有更低的刚性和机械强度。海藻酸胶原海绵的最大应力和杨氏模量最高，分别为0.5463 MPa和0.0086 MPa。带有壳聚糖的胶原蛋白海绵具有更大的断裂伸长率（6.1566％）。抗菌活性最高的海绵是胶原蛋白-壳聚糖混合物，对细菌的抑制区高达46.62％金黄色葡萄球菌。我们预计，基于鱼胶原蛋白和虾壳聚糖的海绵由于其机械和抗菌特性，可以替代生物材料来治愈皮肤伤口。