Data on methods of the synthesis of conformationally restricted analogs of γ-aminobutyric acid (GABA) are systematized in the review. Approaches to the synthesis of different types of conformationally restricted GABA analogs are presented: γ-aminobutenoic acids, aminocycloalkanecarboxylic acids, carboxy-substituted azetidines, prolines, amino acids containing aromatic (heterocyclic including) fragments.

中文翻译：

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构象受限的γ-氨基丁酸类似物的合成

综述了γ-氨基丁酸（GABA）构象受限的类似物的合成方法数据。提出了合成不同类型的构象受限的GABA类似物的方法：γ-氨基丁烯酸，氨基环烷羧酸，羧基取代的氮杂环丁烷，脯氨酸，包含芳族（包括杂环的）片段的氨基酸。