Contemporary microscopic imaging at near-atomic resolution of diverse embodiments in liquid environment has gained keen interest. In particular, Electron Microscopy (EM) can provide comprehensive framework on the structural and functional characterization of samples in liquid phase. In the past few decades, liquid based electron microscopic modalities have developed tremendously to provide insights into various backgrounds like biological, chemical, nanoparticle and material researches. It serves to be a promising analytical tool in deciphering unique insights from solvated systems. Here, the basics of liquid electron microscopy with few examples of its applications are summarized in brief. The technical developments made so far and its preference over other approaches is shortly presented. Finally, the experimental limitations and an outlook on the future technical advancement for liquid EM have been discussed.

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液体电子显微镜：过去、现在和未来

液体环境中不同实施例的近原子分辨率的当代显微成像引起了人们的浓厚兴趣。特别是，电子显微镜 (EM) 可以提供液相样品结构和功能表征的全面框架。在过去的几十年中，基于液体的电子显微镜模式得到了巨大的发展，为生物、化学、纳米颗粒和材料研究等各种背景提供了深入的见解。它是一种很有前途的分析工具，可以破译溶剂化系统的独特见解。在这里，简要总结了液体电子显微镜的基础知识及其应用示例。简要介绍了迄今为止所取得的技术进展及其相对于其他方法的偏好。最后，讨论了液体电镜的实验局限性和未来技术进步的展望。