In this research, gum Arabic (GA) and whey protein nanofibrils (WPN) were employed for the encapsulation of curcumin as a bioactive compound with low water solubility through the complex coacervation method. The optimum conditions for the formation of complex coacervates were found at WPN/GA weight ratio of 1:1 and pH value of 3.0. The resulting complexes showed a high ability for loading of curcumin as a bioactive cargo. Fluorescence spectroscopy showed that the curcumin was loaded in the hydrophobic core of WPN/GA coacervates. The characteristics of curcumin-loaded coacervates were also evaluated by XRD and FT-IR analysis. The curcumin-loaded complex coacervates dispersions showed a shear thinning behavior. They also showed a good surface activity which makes them excellent candidates to fabricate new functional food emulsions and beverages. The results indicated that the antioxidant activity and photo-stability of curcumin were significantly improved by encapsulation into WPN/GA complexes. A sustained-release profile also was investigated for curcumin from WPN/GA complexes in the simulated gastrointestinal conditions. This study suggested that the WPN/GA electrostatic-driven complexes can be used as efficient carriers for curcumin delivery.

中文翻译：

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阿拉伯胶和乳清蛋白纳米纤维制成的姜黄素负载的复合凝聚层的制备与表征

在这项研究中，阿拉伯胶（GA）和乳清蛋白纳米原纤维（WPN）被用于通过复杂凝聚法将姜黄素作为具有低水溶性的生物活性化合物进行囊封。在WPN / GA重量比为1：1和pH值为3.0的条件下，发现了形成复合凝聚层的最佳条件。所得的复合物显示出姜黄素作为生物活性货物的高负载能力。荧光光谱显示姜黄素被装载在WPN / GA凝聚层的疏水核中。还通过XRD和FT-IR分析评估了姜黄素负载的凝聚层的特性。姜黄素负载的复合凝聚层分散体表现出剪切稀化行为。它们还表现出良好的表面活性，使其成为制造新型功能性食品乳液和饮料的极佳候选者。结果表明，通过包裹在WPN / GA复合物中，姜黄素的抗氧化活性和光稳定性得到显着改善。还研究了模拟胃肠道条件下WPN / GA复合物中姜黄素的缓释曲线。这项研究表明，WPN / GA静电驱动复合物可以用作姜黄素递送的有效载体。