Piperaceae plants consist of about 3600 species, of which about 2000 are Piper plants. Their habitat is distributed across pantropical regions. The representative plant is Piper nigrum, known as black pepper. These plants have been widely used in folk medicine in Korean traditional medicine. This review collected papers identifying and separating the amides obtained from these Piper plants, with a focus on Piper amides potential to control the production and growth of fungal strains that cause plant disease and their insecticidal properties against agricultural pests. Piper amide benefits include antiaflatoxigenic activities, antiparasitic activities, anticancer properties, antiplatelet activities, and anti-inflammatory activities, among other therapeutic properties for the treatment of human diseases. In addition, this review paper provides a total synthesis study on the mass production of Piper amides and their derivatives, with a formulation study for industrial use. This review paper is designed to help inform future studies on Piper amide applications.

中文翻译：

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农业和制药业中天然存在的Piper植物酰胺的潜力：胡椒碱和哌隆定的前景

胡椒科植物约有3600种，其中约2000种为胡椒科植物。它们的栖息地分布在整个热带地区。代表性植物是黑胡椒。这些植物已被广泛用于韩国传统医学的民间医学中。这篇综述收集了鉴定和分离从这些Piper植物获得的酰胺的论文，重点是Piper酰胺具有控制导致植物病害的真菌菌株的产生和生长及其对农业害虫的杀虫特性的潜力。哌啶酰胺的益处包括抗黄曲霉毒素活性，抗寄生虫活性，抗癌特性，抗血小板活性和抗炎活性，以及​​用于治疗人类疾病的其他治疗特性。此外，这篇综述文章提供了关于胡椒哌啶酰胺及其衍生物大规模生产的全面综合研究，以及用于工业用途的配方研究。这篇综述文件旨在帮助指导有关Piper酰胺应用的未来研究。