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Synthesis of Pterostilbene through supported-catalyst promoted Mizoroki-Heck reaction, and its transposition in continuous flow reactor
Journal of Flow Chemistry ( IF 2.0 ) Pub Date : 2019-02-18 , DOI: 10.1007/s41981-019-00033-0
Gabriele Laudadio , Graziano Fusini , Gianluca Casotti , Claudio Evangelisti , Gaetano Angelici , Adriano Carpita

Pterostilbene, an important polyphenolic compound with interesting biological activities, has been efficiently synthesized through a Mizoroki-Heck reaction catalyzed by commercially available Pd catalysts immobilized onto heterogeneous supports. The synthesis has been transposed in a continuous flow reactor, following two different retrosynthetic approaches.

Flow synthesis of Pterostilbene



中文翻译:

负载型催化剂促进的咪唑罗基-赫克反应合成紫檀烯及其在连续流反应器中的转位

通过固定在异质载体上的市售Pd催化剂催化的Mizoroki-Heck反应,有效地合成了具有重要生物活性的重要的多酚类化合物。遵循两种不同的逆向合成方法,合成已在连续流反应器中进行了转位。

萜烯的流动合成

更新日期:2019-02-18
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