Background: Mediastinitis after cardiac surgery can lead to devastating consequences such as deep sternal wound infections (DSWI). Staphylococcus epidermidis and other coagulase-negative staphylococci belong to the physiological skin flora and therefore generally are not considered pathogenic agents. Thus, local resistance patterns of these bacterial species often recovered from wound specimens generally are ignored while choosing antibiotics for peri-operative prophylaxis in cardiac surgery as well as in the selection of empiric antibiotic therapy of DSWI.

中文翻译：

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52例连续患者深胸骨伤口感染的临床和微生物学分析

背景：心脏手术后的纵隔炎可导致毁灭性后果，例如深胸骨伤口感染（DSWI）。表皮葡萄球菌和其他凝固酶阴性葡萄球菌属于生理皮肤菌群，因此通常不被视为病原体。因此，在选择用于心脏手术的围手术期预防以及选择DSWI的经验性抗生素治疗的抗生素时，通常会从伤口标本中回收的这些细菌种类的局部耐药性模式通常被忽略。