Background: Cardamom is the flavouring spices mainly cultivated all over the world. Apart from being used as the spice, it has many medicinal values. Therefore, the present study aimed to investigate the potential use of cardamom and its effects on the ability of learning, developmental, and various biochemical factors of Swiss-Webster mice offspring at different stages.

Methods: In this method, Swiss-Webster mice offspring at different stages were used for the analysis of biochemical factors. After the administration of cardamom orally, the pups were subjected to various tests for determining social and defense behaviors of males and females, anxiety behavior; locomotor and neuromuscular activities, haemotological parameters, and hormonal factors of males and females.

Results: The present findings indicate that the cardamom induced reduction in the social and defense behaviors of males and females, respectively, and also anxiety behavior. Interestingly, locomotor and neuromuscular activities decreased significantly.

Discussion: In addition, the packed cell volume, red blood count, hemoglobin content, AChE in forebrain, the testosterone in males and progesterone in females were observed to increase significantly, whereas the blood platelets and total white blood count decreased non-significantly. Through perinatal exposure, cardamom can pass through the placenta or/and lactation and reaches the fetus. Care must be taken when using cardamom and especially during pregnancy and lactation.

Conclusion: The administration of cardamom enhances the ability of social, developmental, and various biochemical factors of Swiss-Webster mice offspring at different stages.

背景：豆蔻是主要在世界各地种植的调味香料。除了用作香料外，它还具有许多药用价值。因此，本研究旨在调查豆蔻的潜在用途及其对不同阶段Swiss-Webster小鼠后代学习，发育和各种生化因子的影响。

方法：采用Swiss-Webster小鼠后代不同阶段进行生化因子分析。口服小豆蔻后，对幼犬进行各种测试，以确定男性和女性的社交和防御行为，焦虑行为。男性和女性的运动和神经肌肉活动，血液学参数和激素因子。

结果：目前的发现表明豆蔻果实分别导致男性和女性的社交和防御行为以及焦虑行为的减少。有趣的是，运动和神经肌肉活动明显减少。

讨论：此外，观察到前额脑的填充细胞体积，红细胞计数，血红蛋白含量，AChE，男性的睾丸激素和女性的孕酮显着增加，而血小板和总白血球计数则无明显下降。通过围产期暴露，豆蔻可以穿过胎盘或/和泌乳并到达胎儿。使用豆蔻时，尤其是在怀孕和哺乳期间，必须小心。

结论：小豆蔻的给药可以增强Swiss-Webster小鼠后代不同阶段的社交，发育和各种生化因子的能力。