We consider designs for cancer trials which allow each medical centre to treat only a limited number of cancer types with only a limited number of drugs. We specify desirable properties of these designs, and prove some consequences. Then we give several different constructions. Finally we generalize this to three or more factors, such as biomarkers.

中文翻译：

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多部分平衡不完全块设计

我们考虑癌症试验的设计，允许每个医疗中心仅用有限数量的药物治疗有限数量的癌症类型。我们指定了这些设计的理想属性，并证明了一些结果。然后我们给出几种不同的构造。最后，我们将其概括为三个或更多因素，例如生物标志物。