Metabolomics provide a qualitative and quantitative overview of the metabolites present in organisms, organs, tissues or specific cells. Different metabolomics approaches have been used for phenotyping populations and, together with mapping methods, allowed the identification of DNA sections associated with metabolite levels, defined as metabolic quantitative trait loci (mQTL). Many studies have provided a large number of mQTL and often candidate genes related to distinct metabolic traits. Since plant growth and development as well as responses to environmental changes lead to metabolic adjustments, the understanding of the genetic bases for metabolite changes is fundamental for plant physiology studies being also highly useful for plant breeding programs. Here, we revisited the progress on metabolite analysis currently used to characterize plant metabolite profile. We further describe few examples of the integration between metabolomic approaches and mapping methods allowing mQTL identification and its importance for plant physiology.

中文翻译：

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从当前的代谢组学方法鉴定代谢物性状

代谢组学提供了生物体，器官，组织或特定细胞中存在的代谢物的定性和定量概述。不同的代谢组学方法已用于表型人群，并与作图方法一起，可以鉴定与代谢物水平相关的DNA片段，定义为代谢定量特征基因座（mQTL）。许多研究已经提供了大量的mQTL，并且经常提供与独特的代谢特性相关的候选基因。由于植物的生长发育以及对环境变化的响应会导致代谢调整，因此了解代谢物变化的遗传基础是植物生理学研究的基础，对植物育种计划也非常有用。这里，我们回顾了目前用于表征植物代谢产物特征的代谢产物分析的进展。我们进一步描述了代谢组学方法与作图方法之间集成的几个例子，这些方法允许mQTL鉴定及其对植物生理的重要性。