Biodentine™ is currently and regularly used as a direct/indirect capping material and dentine substitute under a resin composite direct restoration. The present study investigated the influence of Biodentine™ maturation time on its shear bond strength to a resin-based composite restorative material. One hundred fifty PTFE tubes were divided into 2 groups (n = 75), and each group of tubes was filled with a different substrate material (Biodentine™ or GC Fuji IX glass ionomer cement). The tubes were subsequently divided into subgroups (n = 25) that were used to test different substrate maturation times (early, 12 min; medium, 72 h; and delayed, 2 weeks). A resin-based composite restorative material was bonded to the substrates using a 3-step etch and rinse adhesive system (Optibond FL, Kerr), and the bond was tested for shear bond strength. The Biodentine™/12-min group showed a very low shear bond strength of 2.796 ± 2.704 MPa. The values for the Biodentine™/72-h and Biodentine™/2-weeks groups increased as the maturation time interval increased and were 7.986 ± 2.100 MPa and 10.553 ± 3.281 MPa, respectively. The differences between the Biodentine™/12-min group and the Biodentine™/72-h and Biodentine™/2-weeks groups are statistically highly significant (p < .001). The difference between the Biodentine™/72-h group and the Biodentine™/2-weeks group is statistically significant (p < .05). Bonding with Biodentine™ that has matured for 72 h results in a statistically significant increase in shear bond strength and yields a more clinically acceptable bond between the two materials.

中文翻译：

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硅酸钙基水泥（Biodentine™）的成熟时间对树脂粘结的影响：一项体外研究

目前，Biodentine™在树脂复合材料直接修复的情况下经常用作直接/间接覆盖材料和牙本质替代品。本研究调查了Biodentine™成熟时间对其对基于树脂的复合修复材料的剪切粘合强度的影响。将150根PTFE管分成两组（n = 75），每组管中都填充有不同的基材（Biodentine™或GC Fuji IX玻璃离聚物水泥）。随后将试管分为亚组（n = 25），用于测试不同的底物成熟时间（早12分钟；中度72 h；延迟2周）。使用三步蚀刻和冲洗粘合剂系统（Optibond FL，Kerr）将树脂基复合修复材料粘合到基底上，并测试该粘合的剪切粘合强度。Biodentine™/ 12分钟组的剪切粘结强度非常低，为2.796±2.704 MPa。Biodentine™/ 72-h和Biodentine™/ 2周组的值随着成熟时间间隔的增加而增加，分别为7.986±2.100 MPa和10.553±3.281 MPa。Biodentine™/ 12分钟组与Biodentine™/ 72-h和Biodentine™/ 2周组之间的差异具有统计学意义（p <0.001）。Biodentine™/ 72-h组与Biodentine™/ 2周组之间的差异具有统计学意义（p <.05）。与Biodentine™的结合已经成熟72小时，导致剪切结合强度在统计学上显着提高，并且在两种材料之间产生了临床上更可接受的结合。Biodentine™/ 72-h和Biodentine™/ 2周组的值随着成熟时间间隔的增加而增加，分别为7.986±2.100 MPa和10.553±3.281 MPa。Biodentine™/ 12分钟组与Biodentine™/ 72-h和Biodentine™/ 2周组之间的差异具有统计学意义（p <0.001）。Biodentine™/ 72-h组与Biodentine™/ 2周组之间的差异具有统计学意义（p <.05）。与Biodentine™的结合已经成熟72小时，导致剪切结合强度在统计学上显着提高，并且在两种材料之间产生了临床上更可接受的结合。Biodentine™/ 72-h和Biodentine™/ 2周组的值随着成熟时间间隔的增加而增加，分别为7.986±2.100 MPa和10.553±3.281 MPa。Biodentine™/ 12分钟组与Biodentine™/ 72-h和Biodentine™/ 2周组之间的差异具有统计学意义（p <0.001）。Biodentine™/ 72-h组与Biodentine™/ 2周组之间的差异具有统计学意义（p <.05）。与Biodentine™的结合已经成熟72小时，导致剪切结合强度在统计学上显着提高，并且在两种材料之间产生了临床上更可接受的结合。Biodentine™/ 12分钟组与Biodentine™/ 72-h和Biodentine™/ 2周组之间的差异具有统计学意义（p <0.001）。Biodentine™/ 72-h组与Biodentine™/ 2周组之间的差异具有统计学意义（p <.05）。与Biodentine™的结合已经成熟72小时，导致剪切结合强度在统计学上显着提高，并且在两种材料之间产生了临床上更可接受的结合。Biodentine™/ 12分钟组与Biodentine™/ 72-h和Biodentine™/ 2周组之间的差异具有统计学意义（p <0.001）。Biodentine™/ 72-h组与Biodentine™/ 2周组之间的差异具有统计学意义（p <.05）。与Biodentine™的结合已经成熟72小时，导致剪切结合强度在统计学上显着提高，并且在两种材料之间产生了临床上更可接受的结合。