Evaluation of Anti-inflammatory Effects of Choerospondias axillaris Fruit's Methanolic Extract in Synoviocytes and CIA Rat Model.,Current Pharmaceutical Biotechnology

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Evaluation of Anti-inflammatory Effects of Choerospondias axillaris Fruit's Methanolic Extract in Synoviocytes and CIA Rat Model.
Current Pharmaceutical Biotechnology ( IF 2.2 ) Pub Date : 2020-05-31 , DOI: 10.2174/1389201021666191210114127
Sonia Mann ₁ , Ankita Sharma ₁ , Ashish Sarkar ₁ , Rupsi Kharb ₁ , Rajesh Malhotra ₂ , Barun Datta ₃ , Rajinder K Gupta ₄ , Sagarika Biswas ₁

Affiliation

Background: Rheumatoid Arthritis (RA) is an autoimmune, systemic disease mainly affecting joints. Presently, there is no specific treatment/ drug available for curing RA except few supportive medicines. Therefore, the focus has been shifted to medicinal plants for the treatment of such diseases. Choerospondias axillaris commonly known as Lupsi/Lapsi and has been reported to have several properties for the treatment of various diseases.

Objective: The present study has been conducted to explore the anti-inflammatory effects of Choerospondias axillaris fruit extract on Synoviocytes (FLS) and Collagen-Induced Arthritis (CIA) rat model.

中文翻译：

评价南美酸枣（Cerospondias axillaris）果实的甲醇提取物对滑膜细胞和CIA大鼠模型的抗炎作用。

背景：类风湿关节炎（RA）是一种自身免疫性全身性疾病，主要影响关节。目前，除少数支持药物外，尚无可用于治疗RA的特定治疗方法/药物。因此，焦点已经转移到用于治疗此类疾病的药用植物上。酸枣（Cerospondias axillaris）通常称为Lupsi / Lapsi，据报道具有多种特性，可治疗各种疾病。

目的：本研究旨在探讨南酸枣（Cerospondias axillaris）果实提取物对滑膜细胞（FLS）和胶原诱导性关节炎（CIA）大鼠模型的抗炎作用。

更新日期：2020-05-31

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