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Evaluation of Anti-inflammatory Effects of Choerospondias axillaris Fruit's Methanolic Extract in Synoviocytes and CIA Rat Model.
Current Pharmaceutical Biotechnology ( IF 2.2 ) Pub Date : 2020-05-31 , DOI: 10.2174/1389201021666191210114127
Sonia Mann 1 , Ankita Sharma 1 , Ashish Sarkar 1 , Rupsi Kharb 1 , Rajesh Malhotra 2 , Barun Datta 3 , Rajinder K Gupta 4 , Sagarika Biswas 1
Affiliation  

Background: Rheumatoid Arthritis (RA) is an autoimmune, systemic disease mainly affecting joints. Presently, there is no specific treatment/ drug available for curing RA except few supportive medicines. Therefore, the focus has been shifted to medicinal plants for the treatment of such diseases. Choerospondias axillaris commonly known as Lupsi/Lapsi and has been reported to have several properties for the treatment of various diseases.

Objective: The present study has been conducted to explore the anti-inflammatory effects of Choerospondias axillaris fruit extract on Synoviocytes (FLS) and Collagen-Induced Arthritis (CIA) rat model.


中文翻译:

评价南美酸枣(Cerospondias axillaris)果实的甲醇提取物对滑膜细胞和CIA大鼠模型的抗炎作用。

背景:类风湿关节炎(RA)是一种自身免疫性全身性疾病,主要影响关节。目前,除少数支持药物外,尚无可用于治疗RA的特定治疗方法/药物。因此,焦点已经转移到用于治疗此类疾病的药用植物上。酸枣(Cerospondias axillaris)通常称为Lupsi / Lapsi,据报道具有多种特性,可治疗各种疾病。

目的:本研究旨在探讨南酸枣(Cerospondias axillaris)果实提取物对滑膜细胞(FLS)和胶原诱导性关节炎(CIA)大鼠模型的抗炎作用。
更新日期:2020-05-31
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