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Development of an Implantable Wireless and Batteryless Bladder Pressure Monitor System for Lower Urinary Tract Dysfunction
IEEE Journal of Translational Engineering in Health and Medicine ( IF 3.7 ) Pub Date : 2020-01-01 , DOI: 10.1109/jtehm.2019.2943170
Yihua Zhong 1, 2 , Bolin Qian 3 , Yaguang Zhu 4 , Zhaohui Ren 1, 2 , Junming Deng 1, 2 , Jinghua Liu 1, 2 , Qianrui Bai 1, 2 , Xu Zhang 1, 2
Affiliation  

Background: Closed-loop neuromodulation based on bladder pressure is an effective therapy for lower urinary tract dysfunction. The catheter-based cystometry normally used for bladder pressure measurement is not conducive to patient health because it will bring great mental stress to the patient and increase the risk of infection. Method: This paper designs and implements an implantable wireless and batteryless bladder pressure monitor system that monitors bladder storage in real time by implanting a miniature packaged sensor which transmits the feedback signal to the external receiver through BLE (Bluetooth Low Energy). The implanted part is powered by a dedicated magnetic resonance based wireless power transmission system, which means no battery is needed. Results: The maximum distance to which power can be transmitted is 7cm. The in vitro experiment proves that the system performance can meet the requirement of bladder pressure monitoring. The animal experiment uses rabbits as a model to verify the effectiveness of the system. After implantation, this system can work for a long time without replacing the battery. Conclusion: This system can monitor the pressure of the bladder and provide a basis for Closed-loop neuromodulation in patients with lower urinary tract dysfunction.

中文翻译:


开发用于下尿路功能障碍的植入式无线无电池膀胱压力监测系统



背景:基于膀胱压力的闭环神经调节是治疗下尿路功能障碍的有效方法。通常用于膀胱压力测量的导管膀胱测压会给患者带来很大的精神压力并增加感染风险,不利于患者健康。方法:本文设计并实现了一种植入式无线无电池膀胱压力监测系统,通过植入微型封装传感器实时监测膀胱存储情况,传感器通过BLE(蓝牙低功耗)将反馈信号传输到外部接收器。植入部分由专用的基于磁共振的无线电力传输系统供电,这意味着不需要电池。结果:电力传输的最大距离为7cm。体外实验证明该系统性能能够满足膀胱压力监测的要求。动物实验以兔子为模型,验证了系统的有效性。植入后,该系统可以长时间工作,无需更换电池。结论:该系统可以监测膀胱压力,为下尿路功能障碍患者的闭环神经调节提供依据。
更新日期:2020-01-01
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