Mechanical properties exhibited by the materials used in biomedical device components for articulating joints play an important role in determining the implant performance. In the fabrication of complex-shaped parts, the thermomechanical history experienced in different locations of the final part can be substantially dissimilar, which may lead to large differences in the local microstructures and properties. In many instances, it is not feasible to evaluate experimentally the local mechanical properties in the as-manufactured bioimplant prototypes using standardized tests, and use this information in refining the manufacturing cycle to develop implants with improved performance. In order to bridge this critical gap between materials development and manufacturing, we explore here the use of recently developed spherical indentation stress-strain analysis protocols for the mechanical characterization of local properties in the as-manufactured biomedical device prototype. More specifically, this paper presents two main advances: (i) extension of spherical indentation stress-strain analysis protocols needed to extract reliable estimates of elastic modulus and indentation yield strength from polymer matrix composite (PMC) samples and (ii) demonstration of the differences in the properties between samples produced specifically for the standard tension tests and the as-fabricated PMC acetabular socket prototype intended for total hip joint replacement applications. The results of the present study revealed large differences in the mean and variance of the measured moduli and indentation yield strengths in the acetabular socket and the tensile specimen. Based on the extensive micro-computed tomography (micro-CT) analysis, an attempt has been made to rationalize the local property differences on the basis of microstructural attributes.

中文翻译：

---

使用球形压痕应力-应变协议探测聚合物-陶瓷混合髋臼中的局部力学性能

用于关节的生物医学装置部件中使用的材料所表现出的机械性能在决定植入物性能方面起着重要作用。在制造复杂形状的零件时，在最终零件的不同位置经历的热机械历史可能会大相径庭，这可能会导致局部微结构和性能产生巨大差异。在许多情况下，使用标准化的测试来评估所制造的生物植入物原型中的局部机械性能，并利用此信息完善制造周期以开发性能得到改善的植入物是不可行的。为了弥合材料开发和制造之间的这一重要差距，我们在这里探索使用最新开发的球形压痕应力-应变分析协议，对所制造的生物医学设备原型中的局部特性进行机械表征。更具体地说，本文提出了两个主要进展：（i）扩展球形压痕应力-应变分析协议，以从聚合物基质复合材料（PMC）样品中提取可靠的弹性模量和压痕屈服强度估计值，以及（ii）差异的证明专门为标准拉伸试验生产的样品与旨在用于全髋关节置换应用的预制PMC髋臼窝原型之间的特性。本研究的结果表明，在髋臼窝和拉伸试样中，模量和压痕屈服强度的平均值和方差有很大差异。基于广泛的显微计算机断层扫描（micro-CT）分析，已尝试根据微观结构属性合理化局部属性差异。