The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. Albumin adduct data were compared with aflatoxin M₁ (AFM₁) levels in corresponding milk samples from these cows. The concentration ranged from < LOD to 487.9 pg/mL for AFM₁ and < LOD and 96.3 pg/mg for aflatoxin-albumin. This study indicates that aflatoxin-albumin adducts could be used as a measure of chronic aflatoxin exposure in dairy cattle.

中文翻译：

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血液中黄曲霉毒素-牛血清白蛋白加合物与奶牛牛奶中黄曲霉毒素M1关系的初步研究。

黄曲霉毒素（AF）白蛋白加合物通常用作人类黄曲霉毒素暴露的生物标志物。 在肯尼亚进行的黄曲霉毒素缓解研究中，以前使用的用于人类血液中黄曲霉毒素血清白蛋白的ELISA方法用于分析从奶牛收集的牛血清样品（n = 22）。将这些牛的相应牛奶样品中的白蛋白加合物数据与黄曲霉毒素M ₁（AFM ₁）水平进行比较。对于AFM ₁，浓度范围为<LOD至487.9 pg / mL，对于黄曲霉毒素-白蛋白，浓度范围为<LOD和96.3 pg / mg。这项研究表明，黄曲霉毒素-白蛋白加合物可以用作奶牛中长期黄曲霉毒素暴露的量度。