Objective: Investigating whether intolerance of uncertainty interacts with difficulties in emotion regulation and negative affect in Italian individuals with borderline personality disorder compared to healthy controls. Method: A group of patients with borderline personality disorder (N = 48; clinical group) and a group of healthy participants (N = 48) matched on gender filled-in self-report measures assessing difficulties in emotion regulation, intolerance of uncertainty, and negative affect. Results: Individuals in the clinical group showed higher levels of difficulties in emotion regulation (except for lack of emotional awareness), intolerance of uncertainty, and negative affect than healthy participants. Interestingly, while difficulties in emotion regulation were correlated with negative affect in both groups, significant medium-large correlations between difficulties in emotion regulation and intolerance of uncertainty were observed only in the clinical group. Lastly, findings from a stepwise hierarchical multiple regression analysis conducted on the clinical group revealed that difficulties in emotion regulation were the most significant predictors of negative affect above and beyond IU. Conclusions: Current findings highlight that difficulties in emotion regulation can be intended as a core, high-level process underlying borderline personality disorder and that IU might be involved—although more marginally—in predicting negative affect in this population. Future research further exploring whether and how intolerance of uncertainty and difficulties in emotion regulation interact in borderline personality disorder may inform psychological assessment and treatment.

中文翻译：

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情绪调节困难和对不确定性的不容忍是否与边缘型人格障碍的负面影响有关？

目的：调查与健康对照相比，意大利边缘型人格障碍患者的不确定性不容忍是否与情绪调节困难和负面影响相互作用。方法：一组边缘型人格障碍患者（N = 48；临床组）和一组健康参与者（N = 48）在评估情绪调节困难、对不确定性的不容忍和负面影响。结果：与健康参与者相比，临床组中的个体在情绪调节（除了缺乏情绪意识）、对不确定性的不容忍和负面影响方面表现出更高水平的困难。有趣的是，虽然情绪调节的困难与两组的负面情绪相关，仅在临床组中观察到情绪调节困难和对不确定性的不容忍之间存在显着的中大相关性。最后，对临床组进行的逐步分层多元回归分析的结果表明，情绪调节困难是 IU 以外负面影响的最重要预测因素。结论：目前的研究结果强调，情绪调节的困难可以作为边缘型人格障碍潜在的核心、高级过程，并且 IU 可能参与（尽管更轻微）预测该人群的负面影响。