Temperature estimation of inflamed bowel by the photoacoustic inverse approach.,International Journal for Numerical Methods in Biomedical Engineering

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Temperature estimation of inflamed bowel by the photoacoustic inverse approach.
International Journal for Numerical Methods in Biomedical Engineering ( IF 2.2 ) Pub Date : 2020-01-10 , DOI: 10.1002/cnm.3300
Mohsen Alaeian ₁ , Helcio R B Orlande ₁ , João Carlos Machado _{2,

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Affiliation

Local temperature increase is one of the five classical signs of regions with inflammations. This work is focused on the application of the photoacoustic technique for the estimation of the temperature field in the colon, as the solution of an inverse problem, for the detection of inflamed regions. Two‐dimensional cases are examined here involving a cross section of the bowel, which characterize either the inflammation of the whole mucosa layer, or three small inflamed regions. The inverse problem is solved for a rotating laser inside the intestine lumen, which imposes pulses for the generation of the acoustic waves. One single ultrasound detector, also located at the laser rotating shaft, provides the simulated measurements for the inverse analysis. The inverse problem is solved here with the minimization of the maximum a posteriori objective function. Results show that the proposed technique can be applied for accurate estimations of the temperature distribution in the region of interest, which might be used for the diagnosis of inflammatory bowel diseases (IBD).

中文翻译：

用光声逆方法估算发炎的肠的温度。

局部温度升高是发炎区域的五个经典标志之一。这项工作专注于光声技术在结肠温度场估计中的应用，作为反问题的解决方案，用于检测发炎区域。在此检查涉及肠横断面的二维病例，其特征是整个粘膜层或三个小发炎区域的炎症。对于肠腔内部的旋转激光器，解决了反问题，该激光器施加脉冲以产生声波。同样位于激光旋转轴上的单个超声波检测器为反分析提供了模拟的测量结果。在此，通过最大后验目标函数的最小化来解决反问题。结果表明，所提出的技术可用于感兴趣区域温度分布的准确估计，可用于诊断炎症性肠病（IBD）。

更新日期：2020-01-10

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