For cell culture scaffold innovation, 3DPVS, namely 3D printed vibratory scaffold, was indicated as a future novel product, and it currently stands at conceptual development stage. One essential part for 3DPVS design is innovation, and TRIZ (algorithm of inventive problem solving) was studied as promising method for generating novel conceptual solutions. This study targets designing and solving 3DPVS problems using TRIZ in the new biodimension. We aim to utilize TRIZ to conduct a multi-layer problem-solving process, which is to address design concerns of 3DPVS, especially at super-system to system level. In this connection, TRIZ is used to address basic constraints and contradictions inside regarding trinity of 3D printing, 3D scaffold and bio-based vibratory functionality. In the study, five basic conceptual solutions for potential 3DPVS, namely magnetic, electric, mechanical, light and thermal based, have been generated. A brief evaluation has also been conducted, where magnetic-based 3DPVS shows the relatively highest applicability as potential 3DPVS. Compared with traditional experimental-oriented processes for biodesign, the approach of utilizing TRIZ can be inspiring and reinvigorating, which prepares a ground for future 3DPVS design to address detailed sub-system concerns. This study might, to some extent, fill a gap in scaffold design and TRIZ literature and hopefully provide a comprehensive perspective of a timely topic.

中文翻译：

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利用TRIZ生成3DPVS的基本概念解决方案

对于细胞培养支架创新，3DPVS（即3D打印振动支架）被指示为未来的新产品，目前处于概念开发阶段。3DPVS设计的一个基本部分是创新，而TRIZ（创造性问题解决算法）被研究为产生新颖概念解决方案的有前途的方法。这项研究的目标是在新的生物维度中使用TRIZ设计和解决3DPVS问题。我们的目标是利用TRIZ进行多层问题解决，以解决3DPVS的设计问题，尤其是在超级系统到系统级。在这方面，TRIZ用于解决内部有关3D打印，3D支架和基于生物的振动功能的三重性的基本约束和矛盾。在研究中，针对潜在3DPVS的五个基本概念解决方案，即产生了基于磁，电，机械，光和热的信息。还进行了简短的评估，其中基于磁性的3DPVS作为潜在的3DPVS显示出相对最高的适用性。与传统的面向实验的生物设计过程相比，利用TRIZ的方法可以启发和振兴，这为将来3DPVS设计解决详细子系统问题奠定了基础。这项研究可能在某种程度上填补了脚手架设计和TRIZ文献中的空白，并希望为及时主题提供一个全面的视角。与传统的面向实验的生物设计过程相比，利用TRIZ的方法可以启发和振兴，这为将来3DPVS设计解决详细子系统问题奠定了基础。这项研究可能在某种程度上填补了脚手架设计和TRIZ文献中的空白，并希望为及时主题提供一个全面的视角。与传统的面向实验的生物设计过程相比，利用TRIZ的方法可以启发和振兴，这为将来3DPVS设计解决详细子系统问题奠定了基础。这项研究可能在某种程度上填补了脚手架设计和TRIZ文献中的空白，并希望为及时主题提供一个全面的视角。