In order to reduce the damage to tissue and fill the interstices between fibers, multifilament sutures are frequently treated with certain coating materials. The objective of this study was to create and characterize dopamine hydrochloride (DA) and carboxymethyl chitosan (CMCS) coatings on surgical sutures and investigate their effects on the frictional performance of the surgical sutures during sliding through a skin substitute. The effects of the treatment on the physical and chemical characteristics of the surgical sutures were evaluated. The friction force of the surgical sutures during sliding through the skin substitute was experimentally determined using a penetration friction apparatus. The coefficient of friction (COF) was calculated using a linear elastic model and was used to estimate the frictional behavior of the surgical suture-skin interactions.The results showed that the DA coating could evenly deposit on the surface of the etched multifilament surgical suture surfaces in a weakly alkaline buffer solution. The CMCS coating material could form a uniform film on the surface of the sutures. Minor changes in the surface roughness of the multifilament surgical sutures with different treatments occurred in this study. The friction force and the COF of the multifilament surgical sutures with DA and CMCS coating showed little change when compared with untreated multifilament surgical sutures.

中文翻译：

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用于多丝外科缝合线的多巴胺盐酸盐和羧甲基壳聚糖涂层及其与皮肤替代物滑动接触时对摩擦的影响

为了减少对组织的损害并填充纤维之间的间隙，经常用某些涂层材料处理复丝缝合线。这项研究的目的是创建和表征手术缝线上的多巴胺盐酸盐（DA）和羧甲基壳聚糖（CMCS）涂层，并研究它们在通过皮肤替代物滑动期间对手术缝线摩擦性能的影响。评价了该处理对手术缝合线的物理和化学特性的影响。使用穿透摩擦装置通过实验确定了在穿过皮肤替代物滑动期间外科缝合线的摩擦力。用线性弹性模型计算摩擦系数（COF），并用于估计手术缝线与皮肤相互作用的摩擦行为，结果表明DA涂层可以均匀地沉积在蚀刻的多丝手术缝线表面上在弱碱性缓冲溶液中。CMCS涂层材料可以在缝合线的表面上形成均匀的膜。在这项研究中发生了不同处理的复丝手术缝合线表面粗糙度的微小变化。与未处理的复丝手术缝合线相比，涂有DA和CMCS涂层的复丝手术缝合线的摩擦力和COF几乎没有变化。结果表明，在弱碱性缓冲溶液中，DA涂层可以均匀地沉积在蚀刻的复丝手术缝合线表面上。CMCS涂层材料可以在缝合线的表面上形成均匀的膜。在这项研究中发生了不同处理的复丝手术缝线表面粗糙度的微小变化。与未处理的复丝手术缝合线相比，涂有DA和CMCS涂层的复丝手术缝合线的摩擦力和COF几乎没有变化。结果表明，在弱碱性缓冲溶液中，DA涂层可以均匀地沉积在蚀刻的复丝手术缝合线表面上。CMCS涂层材料可以在缝合线的表面上形成均匀的膜。在这项研究中发生了不同处理的复丝手术缝线表面粗糙度的微小变化。与未处理的复丝手术缝合线相比，涂有DA和CMCS涂层的复丝手术缝合线的摩擦力和COF几乎没有变化。