Abstract The present investigation reports the synthesis of graphene oxide–polyvinyl poly pyrrolidone composite and its application in the extraction of aflatoxins in food samples. This composite was successfully synthesized and characterized with analytical instruments such as UV–Vis, FITR, XRD, and SEM techniques. The extraction was carried out by reinforced hollow fiber liquid-phase microextraction coupled with high-performance liquid chromatography (HPLC). Various parameters that affect the productivity of the present technique were exhaustively explored, and the quantifications were carried out under the optimized states. The limits of detection (LODs) were found to be 0.33, 0.10, 0.37, and 0.10 ng g −1 , and limits of quantification (LOQs) were 1.10, 0.33, 1.24, and 0.33 ng g −1 , respectively, for aflatoxins B 1 , B 2 , G 1 , and G 2 . The accuracy of the present method was determined based on the relative recovery (RR%) of the aflatoxins and the RR% of aflatoxins B 1 , B 2 , G 1 , and G 2 which were found to be quite good (between 60.20 and 108.20 for 1 ng g −1 and between 62.02 and 95.39 for 5 ng g −1 ) in food samples. Applicability of the sorbent for the separation and quantification of the above-mentioned aflatoxins from food samples were examined. The developed method is straightforward, reliable, and effective, and has been successfully applied in determination of aflatoxins from food samples. Graphic abstract

中文翻译：

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氧化石墨烯-聚乙烯聚吡咯烷酮-中空纤维固相微萃取法净化食品样品中的黄曲霉毒素

摘要 本研究报道了氧化石墨烯-聚乙烯基聚吡咯烷酮复合物的合成及其在食品样品中黄曲霉毒素提取中的应用。该复合材料已成功合成并使用分析仪器（如 UV-Vis、FITR、XRD 和 SEM 技术）进行表征。萃取采用增强型中空纤维液相微萃取结合高效液相色谱法(HPLC)。对影响本技术生产率的各种参数进行了详尽的探索，并在优化状态下进行了量化。黄曲霉毒素 B 的检测限 (LOD) 分别为 0.33、0.10、0.37 和 0.10 ng g -1 ，定量限 (LOQ) 分别为 1.10、0.33、1.24 和 0.33 ng g -1 1、B 2 、G 1 和G 2 。本方法的准确度是基于黄曲霉毒素的相对回收率 (RR%) 和黄曲霉毒素 B 1 、B 2 、G 1 和 G 2 的 RR% 确定的，发现它们非常好（在 60.20 和 108.20 之间）食品样品中 1 ng g -1 和 62.02 至 95.39 之间（5 ng g -1 ）。检测了该吸附剂用于从食品样品中分离和定量上述黄曲霉毒素的适用性。该方法简单、可靠、有效，已成功应用于食品样品中黄曲霉毒素的测定。图形摘要 39 为 5 ng g -1 ) 食品样品。检测了该吸附剂用于从食品样品中分离和定量上述黄曲霉毒素的适用性。该方法简单、可靠、有效，已成功应用于食品样品中黄曲霉毒素的测定。图形摘要 39 为 5 ng g -1 ) 食品样品。检测了该吸附剂用于从食品样品中分离和定量上述黄曲霉毒素的适用性。该方法简单、可靠、有效，已成功应用于食品样品中黄曲霉毒素的测定。图形摘要