Vulnerable and Resilient Cognitive Performance Related to Early Life Stress: The Potential Mediating Role of Dopaminergic Receptors in the Medial Prefrontal Cortex of Adult Mice,International Journal of Developmental Neuroscience

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Vulnerable and Resilient Cognitive Performance Related to Early Life Stress: The Potential Mediating Role of Dopaminergic Receptors in the Medial Prefrontal Cortex of Adult Mice
International Journal of Developmental Neuroscience ( IF 1.7 ) Pub Date : 2020-01-23 , DOI: 10.1002/jdn.10004
Saulo G Tractenberg ₁ , Rodrigo Orso ₂ , Kerstin C Creutzberg ₂ , Luiza M C Malcon ₁ , Francisco S Lumertz ₁ , Luis Eduardo Wearick-Silva ₂ , Thiago W Viola ₂ , Marco A Riva ₃ , Rodrigo Grassi-Oliveira _{1,

2}

Affiliation

Exposure to early life stress (ELS) is known to have pronounced effects on the prefrontal cortex (PFC). However, not all individuals exposed to ELS manifest the same neurobiological and cognitive phenotypes when adults. Dopamine signaling could be a key factor in understanding the effects of stress on PFC‐related cognitive function.

中文翻译：

与早期生活压力相关的脆弱和有弹性的认知表现：多巴胺能受体在成年小鼠内侧前额叶皮层中的潜在中介作用

众所周知，早年生活压力 (ELS) 会对前额叶皮层 (PFC) 产生显着影响。然而，并非所有暴露于 ELS 的个体在成年时都表现出相同的神经生物学和认知表型。多巴胺信号可能是了解压力对 PFC 相关认知功能影响的关键因素。

更新日期：2020-01-23

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