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Surface texture evaluation of additively manufactured metallic cellular scaffolds for acetabular implants using X-ray computed tomography
Bio-Design and Manufacturing ( IF 8.1 ) Pub Date : 2019-05-22 , DOI: 10.1007/s42242-019-00042-x
Shan Lou , Luca Pagani , Wenhan Zeng , Muhammad U. Ghori , Xiangqian Jiang , Paul J. Scott

The surface topography of acetabular implants plays a key role in providing cell attachment and proliferation. The measurement and characterisation of the surface texture of the cellular scaffold layer on the acetabular cup are very difficult due to the 3D nature of scaffold geometry. It is proposed to use X-ray computed tomography (XCT) to measure the surface texture of an electron beam melting-produced titanium acetabular cup. The surface texture of its cellular scaffold is evaluated using the newly developed 3D surface texture parameters, which allows surface characterisation on 3D triangular mesh surfaces. Four commonly used height parameters, i.e. the arithmetical mean height Sa, the root mean square height Sq, the skewness Ssk and the kurtosis Sku, are calculated from surface patches extracted from the XCT scanned triangular mesh surface. In addition, the surface peak density and pit density, which are more related to cell communication and proliferation, are estimated based on the 3D watershed segmentation. The Wolf pruning with an empirical threshold 12 µm is used to control the over-segmentation.

中文翻译:

使用X射线计算机断层摄影术评估用于髋臼植入物的增材制造的金属细胞支架的表面纹理评估

髋臼植入物的表面形貌在提供细胞附着和增殖中起关键作用。由于支架几何结构的3D性质,很难对髋臼杯上的细胞支架层的表面纹理进行测量和表征。提出使用X射线计算机断层摄影术(XCT)来测量电子束熔融产生的钛髋臼杯的表面纹理。使用新开发的3D表面纹理参数评估其细胞支架的表面纹理,该参数允许在3D三角形网格表面上进行表面表征。从XCT扫描的三角形网格表面提取的表面补丁计算出四个常用的高度参数,即算术平均高度Sa,均方根高度Sq,偏度Ssk和峰度Sku。此外,基于3D分水岭分割估计与细胞传播和增殖更相关的表面峰密度和凹坑密度。经验阈值为12 µm的Wolf修剪用于控制过度细分。
更新日期:2019-05-22
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