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Hybrid material of structural DNA with inorganic compound: synthesis, applications, and perspective
Nano Convergence ( IF 13.4 ) Pub Date : 2020-01-06 , DOI: 10.1186/s40580-019-0211-4
Seung Won Shin 1 , Ji Soo Yuk 1 , Sang Hun Chun 1 , Yong Taik Lim 1, 2 , Soong Ho Um 1, 2
Affiliation  

Owing to its precise manipulation in nanoscale, DNA as a genetic code becomes a promising and generic material in lots of nanotechnological outstanding exploitations. The nanoscale assembly of nucleic acids in aqueous solution has showed very remarkable capability that is not achievable from any other material resources. In the meantime, their striking role played by effective intracellular interactions have been identified, making these more attractive for a variety of biological applications. Lately, a number of interesting attempts have been made to augment their marvelous diagnostic and therapeutic capabilities, as being integrated with inorganic compounds involving gold, iron oxide, quantum dot, upconversion, etc. It was profoundly studied how structural DNA-inorganic hybrid materials have complemented with each other in a synergistic way for better-graded biological performances. Such hybrid materials consisting of both structural DNAs and inorganics are gradually receiving much attention as a practical and future-oriented material substitute. However, any special review articles highlighting the significant and innovative materials have yet to be published. At the first time, we here demonstrate novel hybrid complexes made of structural DNAs and inorganics for some practical applications.

中文翻译:

结构DNA与无机化合物的杂化材料:合成、应用和前景

由于其在纳米尺度上的精确操作,DNA 作为一种遗传密码,成为许多纳米技术杰出开发中一种有前景的通用材料。核酸在水溶液中的纳米级组装已显示出任何其他材料资源无法实现的非常显着的能力。与此同时,它们通过有效的细胞内相互作用所发挥的显着作用已被确定,这使得它们对于各种生物应用更具吸引力。最近,人们进行了许多有趣的尝试,以增强其奇妙的诊断和治疗能力,例如与金、氧化铁、量子点、上转换等无机化合物相结合。人们深入研究了结构 DNA-无机杂化材料如何以协同方式相互补充,以获得更好的生物学性能。这种由结构DNA和无机物组成的杂化材料作为一种实用且面向未来的材料替代品逐渐受到人们的关注。然而,任何强调重要和创新材料的特别评论文章尚未发表。我们在这里首次展示了由结构 DNA 和无机物制成的新型杂化复合物,用于一些实际应用。
更新日期:2020-01-06
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