Biofilm formation of pathogenic bacteria in medical devices plays an important role in the development of chronic infections. The increased use of medical implants in health care is strongly associated with elevated biofilm-related infections. S. aureus is one of the most frequent agents causing hospital-acquired catheter-related bloodstream infections (CRBSI) associated with biofilm formation.¹ In 2017, approximately 120,000 cases of S. aureus bloodstream infections occurred and led to approximately 20,000-associated deaths in the United States.²

中文翻译：

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环境因素调节金黄色葡萄球菌生物膜的形成

医疗器械中致病菌生物膜的形成在慢性感染的发展中起着重要作用。医疗植入物在医疗保健中的使用增加与生物膜相关感染的增加密切相关。金黄色葡萄球菌是引起与生物膜形成相关的医院获得性导管相关血流感染 (CRBSI) 的最常见病原体之一。¹ 2017 年，美国发生了约 120,000 例金黄色葡萄球菌血流感染病例，并导致约 20,000 人死亡。²