The microbiota is indispensable for human health and the regulation of various body functions, including energy metabolism. The harmonic crosstalk between the microbiota and the intestinal epithelial barrier determines gut homeostasis and health status in the healthy subject. Obesity and type 2 diabetes risk are, to some extent, explained by alterations in the microbiota. Since recent data indicate that the population of gut microorganisms can influence nutrient absorption and energy storage thus prevalence on obesity and metabolic disorders. Moreover, metabolic disease conditions, such as obesity, may be stimulated by genetic, environmental factors and by pathways that link metabolism with the immune system. On the basis of the above considerations, this review compiles the current results obtained in recent studies indicating the gut microbiota contribution to obesity development.

中文翻译：

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膳食纤维和益生元通过调节肠道菌群对肥胖的调节作用

微生物群对于人体健康和各种身体功能（包括能量代谢）的调节都是必不可少的。微生物群与肠上皮屏障之间的谐波串扰决定了健康受试者的肠道稳态和健康状况。在某种程度上，肥胖和2型糖尿病的风险可以通过微生物群的改变来解释。由于最近的数据表明肠道微生物种群可以影响营养吸收和能量存储，因此普遍存在于肥胖和代谢疾病中。此外，遗传，环境因素以及将新陈代谢与免疫系统联系起来的途径可能会刺激代谢性疾病，例如肥胖。基于以上考虑，