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N -Halamine Functionalized Electrospun Poly(Vinyl Alcohol- co -Ethylene) Nanofibrous Membranes with Rechargeable Antibacterial Activity for Bioprotective Applications
Advanced Fiber Materials ( IF 17.2 ) Pub Date : 2019-08-19 , DOI: 10.1007/s42765-019-00008-9 Mingguang Liang , Fei Wang , Mei Liu , Jianyong Yu , Yang Si , Bin Ding
中文翻译:
具有可充电抗菌活性的N-哈拉明功能化电纺丝聚(乙烯醇-乙烯-乙烯)纳米纤维膜,具有生物保护作用。
更新日期:2019-08-19
Advanced Fiber Materials ( IF 17.2 ) Pub Date : 2019-08-19 , DOI: 10.1007/s42765-019-00008-9 Mingguang Liang , Fei Wang , Mei Liu , Jianyong Yu , Yang Si , Bin Ding
Abstract
Developing bioprotective materials with bactericidal activity is of great significance since it can effectively keep healthcare workers from infection by emerging infectious diseases; however, this is still a big challenge. Herein, we fabricate a novel rechargeable N-halamine antibacterial material by functionalizing electrospun poly(vinyl alcohol-co-ethylene) (EVOH) nanofibers with dimethylol-5,5-dimethylhydantoin (DMDMH). The premise of the design is that the N-halamine compound, DMDMH, can be covalently grafted on the nanofibers, endowing the EVOH nanofibrous membranes (ENM) with rechargeable and durable bactericidal activity. The as-prepared DMDMH functionalized ENM (EDNM) render rechargeable chlorination capacity (> 2000 ppm), high inactivation efficacy against bacteria (> 99.9999% within 3 min), high filtration efficiency (> 99.5%) under low air resistance, and robust mechanical properties, which are due to the synergistic effect of the unique characters of N-halamines and electrospun nanofibrous architecture. The successful synthesis of the N-halamine antibacterial membranes can serve as a functional layer of protective equipment that capable of inactivating and intercepting pathogenic bioaerosols, providing new ways into the development of new-generation antibacterial bioprotective materials.Graphic Abstract
中文翻译:
具有可充电抗菌活性的N-哈拉明功能化电纺丝聚(乙烯醇-乙烯-乙烯)纳米纤维膜,具有生物保护作用。