In this study, borosilicate bio-glass (BG) was incorporated into magnesium phosphate cement (MPC) for the purpose of developing an injectable and bioactive composite cement with suitable physicochemical and biocompatible performance. Results show that the BG-incorporated MPC possesses an excellent injectability, and can be used to fill in different 3D printed defect models using a syringe with a moderate setting time. Meanwhile, BG can retard the setting time and adjust the exothermic temperature of MPC. When the MPC/BG ratio was 3:1 (MPC3-BG), its corresponding setting time, peak temperature, anti-washout ratio and compressive strength were 9.9 ± 0.7 min, 45.8 ± 1.6 °C, 87%–90% and 13.5 MPa, respectively, which were suitable for injection and bone reparation. Characterizations of MPC3-BG showed that it had a faster degradation rate than MPC and the functional ions of boron and silicon could be released from the dissolution of the composite cement. In vitro and in vivo...

中文翻译：

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使用硼硅酸盐生物玻璃掺入磷酸镁，具有适中凝固时间和温度的可注射和生物活性骨水泥。

在这项研究中，硼硅酸盐生物玻璃 (BG) 被掺入磷酸镁水泥 (MPC) 中，目的是开发具有合适物理化学和生物相容性性能的可注射和生物活性复合水泥。结果表明，掺入 BG 的 MPC 具有出色的可注射性，可用于使用注射器以适中的凝固时间填充不同的 3D 打印缺陷模型。同时BG可以延缓凝结时间，调节MPC的放热温度。当MPC/BG比为3:1（MPC3-BG）时，其对应的凝结时间、峰值温度、抗冲刷比和抗压强度分别为9.9±0.7min、45.8±1.6℃、87%~90%和13.5 MPa，分别适用于注射和骨修复。MPC3-BG 的表征表明，它比 MPC 具有更快的降解速率，并且硼和硅的功能离子可以从复合水泥的溶解中释放出来。体外和体内...