DNA methylation-based epigenetic signatures have become valuable cancer biomarkers. We highlight the advantages of liquid biopsy based DNA-methylation profiling for noninvasive diagnosis of early stage cancers and discuss the advanced analytical approaches developed by commercial and academic partnerships.

中文翻译：

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DNA甲基化分类器对癌症早期检测的诊断能力。

基于DNA甲基化的表观遗传学特征已经成为有价值的癌症生物标志物。我们重点介绍了基于液体活检的DNA甲基化谱图对早期癌症进行非侵入性诊断的优势，并讨论了由商业和学术合作伙伴开发的高级分析方法。