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Surgical management of anterior skull-base malignancies (endoscopic vs. craniofacial resection).
Journal of Neuro-Oncology ( IF 3.2 ) Pub Date : 2020-02-04 , DOI: 10.1007/s11060-020-03413-y
Thiago Albonette-Felicio 1, 2 , Gustavo G Rangel 2, 3, 4 , Rafael Martinéz-Pérez 1, 2 , Douglas A Hardesty 1, 2 , Ricardo L Carrau 2, 3 , Daniel M Prevedello 1, 2
Affiliation  

Anterior skull base (ASB) malignancies are rare entities characterized by delayed diagnosis and comprise a variety of distinct histological types. Their treatment involves clinical and surgical management, with the latter encompassing open and, more recently, endoscopic approaches. The craniofacial resection, as an open approach, has revolutionized the treatment of such diseases and is the gold standard, although significant morbidity and facial scars are a shortcoming. Seeking a less invasive alternative, many surgeons have approached these pathologies using the endoscopic endonasal approach, with the theoretical advantage of reduced morbidity and no facial scars. In this manuscript, we aim to review the current state-of-art in the surgical management of the ASB malignancies. As such, indications, limitations and future perspectives of different surgical techniques are discussed.



中文翻译:

前颅底恶性肿瘤的手术治疗(内窥镜与颅面切除术)。

前颅底 (ASB) 恶性肿瘤是罕见的实体,其特征是诊断延迟,包括多种不同的组织学类型。他们的治疗包括临床和手术治疗,后者包括开放式和最近的内窥镜方法。颅面切除术作为一种开放式方法,彻底改变了此类疾病的治疗方法,是金标准,尽管显着的发病率和面部疤痕是一个缺点。为了寻求一种侵入性较小的替代方案,许多外科医生已经使用内窥镜鼻内入路来处理这些病理,其理论优势是降低发病率和无面部疤痕。在这份手稿中,我们旨在回顾 ASB 恶性肿瘤手术治疗的最新进展。因此,迹象表明,

更新日期:2020-02-04
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