INTRODUCTION Glioma surgery near the functional area is still a dilemma. Intraoperative neurophysiologic monitoring (IONM) and functional mapping can play a role to maximize the extent of resection (EOR), while minimizing the risk of sequelae. We herein review the utility of tailored intraoperative mapping and monitoring in patients undergoing glioma surgery in our institute. METHODS Patients were divided into two groups on the basis of application tailored IONM (group A, 2013-2017, n = 53) or not (group B, 2008-2012, n = 49) between January 2008 and December 2017. The setup, tailored IONM protocols, surgery, and clinical results of all patients with eloquent glioma were analyzed with the EOR, functionality scores, overall survival (OS) and progression-free survival (PFS) retrospectively. RESULTS The 102 patients were considered eligible for analysis. High grade and low grade gliomas accounted for 73 (72%) and 29 (28%) cases, respectively. There was a positive association between the application of neuromonitor and post-operative functional preservation, but no significant statistical differences over the EOR, OS and PFS between the two groups. CONCLUSIONS In our experience, tailored intraoperative functional mapping provides an effective neurological function preservation. Routine implementation of neurophysiological monitoring with adequate pre-operative planning and intraoperative teamwork in eloquent glioma can get more satisfied functional preservation. Due to the maturation and experience of our IONM team may also be the variation factor, prospective studies with a more prominent sample and proper multivariate analysis will be expected to determine the real benefit.

中文翻译：

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定制的术中神经生理学监测在神经胶质瘤手术中的作用：单一机构的经验。

引言功能区附近的胶质瘤手术仍然是一个难题。术中神经生理监测（IONM）和功能映射可发挥最大作用，在最大程度地减少切除（EOR）的同时，将后遗症的风险降至最低。我们在这里回顾了在我所进行的神经胶质瘤手术患者中定制的术中作图和监测的实用性。方法在2008年1月至2017年12月之间，根据应用定制的IONM将患者分为两组（A组，2013-2017，n = 53）（否）（B组，2008-2012，n = 49）。回顾性分析了所有雄辩性神经胶质瘤患者的定制IONM方案，手术和临床结果，并对其EOR，功能评分，总生存期（OS）和无进展生存期（PFS）进行了分析。结果102例患者被认为符合分析条件。高度和低度神经胶质瘤分别占73例（72％）和29例（28％）。神经监测器的应用与术后功能保存之间存在正相关，但两组之间在EOR，OS和PFS方面无显着统计学差异。结论根据我们的经验，量身定制的术中功能图提供了有效的神经功能保存。在雄辩性神经胶质瘤中常规实施神经生理学监测以及适当的术前计划和术中团队合作，可以更满意地保留功能。由于我们IONM团队的成熟和经验也可能是差异因素，